Hello all-
Long story short....this cycle, my first on injectables.....I overresponded to the meds.....produced 5 follicles same size....went back for another u/s only 3 were then maturing, good I thought, but no, so many smaller ones were causing my E2 to become too high.....they reduced the dose of my meds, and I had an u/s and bw on tuesday, revealing YAY, my E2 dropped....but today's u/s and bloodwork reveal my E2 continues to drop....not even 300 at this point...and I noticed at my u/s that there was very little growth with the follicles. Is there any hope for this cycle? They increased my dose of gonal f tonight, and I go in for bw tomorrow AM, they will call w/ results in the afternoon.

Did anybody experience, this complete up and down roller coaster? If they do cancel what happens? Do the follicles just never reach maturity? You never ovulate? I feel like I need a medical degree to digest all of this. I don't think there are any more tears left in me.......and then boom, more disappointing news, more tears....I want to at least have a chance after all this heartache and effort, to have not have a chance is too much to bare...well thanks for your help!

Katie

Katie, I haven't done an injectables cyle, but my last clomid IUI cycle, I had to go in 4 times for them to chart my follicle size. And I thought I would lose my mind. I had like 4 good size follicles--and then on the last u/s the nurse found 2. and she said "where did they all go?" of course, i was thinking 'this is never good to hear your dr say.' but then she say what meds i was on and said "oh, with the estrogen its normal for one to become dominant and the others just stop maturing."

so, I certainly know the tears and the frustration. You should definitely bd still--and even if they happen to cancel the IUI, you still can get lucky and have a bfp.

remember as their upping your dosage, etc., its all hormones so it really plays into our emotions. So let yourself feel and cry if you need to , but stay positive!

we're all here to help!

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DD Born 2/18/2008

I was on basically the same protcol as you - bcp's and lupron. When I started stimming, I was oversuppressed. My follies did not start growing until like cd13! I stimmed for 18 days straight! Mid-cycle I begged my doctor to cancel me because I went through boxes of 450 iu gonal f...and only had 3 left...enough for 2 of my normal cycles. He kept plugging away and they finally started growing. I think what did the trick was I stimmed in the morning and at night.

You will be okay...I think your ovaries are being stubborn! Hopefully they will start to cooperate!

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I overresponded many times. i think they canceled 3-4 cycles for me. It made me so mad. and yes I have gone through the roller coaster thing but they were usually too late to fix the problem. Sounds like they caught it for you. I always had to tell them to do early b/w becasue I would get mature follies around cd 8.

Good luck,

Dani

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