I can only tell you what Clomid did for me...I didn't experience a lot of side effects other than headaches. It did however, hyperstimulate my ovaries and produced 3 cysts. Just be sure that your wife is closely monitored while being on it. If I were monitored better they couldv'e take me off or reduced the dose and the cysts wouldn't have appeared.
Is her fertility doc or ob giving her the Rx? Also just as a warning, Clomid can make some women evil so just take it!

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Jaime(31)-DH(41)
9/29-12/10 4 failed IUI's--2 natural, 2 Clomid
2/16-4/13 BCP's
4/7 Begin Lupron
4/23 Begin Gonal F and Menopur
5/3 Egg Retrieval 8:15
5/8 Egg Transfer (2 5day blasts)
5/17 BETA DAY=BFP 241 9dp5dt
5/24 2nd Beta= 9,239 16dp5dt