Hello...
I was just lurking and saw no one had responded to your post yet so thought I'd offer my 2 cents (I have PCOS and insulin resistance as well). Anyways, in response to your insulin resistance(IR) question, IR is a problem where your body doesn't respond to the insulin in the right way causing your body to produce too much insulin. That's the simplified version. Metformin and Glucophage are the same med...one is generic, one isn't. A lot of women who have IR or PCOS get PG on this med. without any other intervention. Gluc/Met does cause some bathroom problems, but they usually are worked out after taking the med for a while or adjusting your dose. Good luck and I hope that your RE figures this out for you.

Karen